A new application form of autologous plasma, obtained by means of Plasmolifting technology, was developed and then patented: Plasmolifting Powder. In the course of pilot studies, a high efficacy of Plasmolifting Powder for the treatment of inflammatory processes of the upper respiratory tract, the nasal mucosa and the paranasal sinuses as well as the safety of its use and its high bioavailability were confirmed.
Application protocols of Plasmolifting technology have been developed for various medical fields, including dentistry, cosmetology, trichology, orthopedics, traumatology, sports medicine, urology and gynecology. A number of research projects dealing with the application of plasmolifting technology have been published in scientific journals. Plasmolifting Gel and Plasmolifting Serum were added to the product range.
Speech on 1st International Scientific and Practical Conference on Esthetic Medicine in Israel. The first results of the application of Plasmolifting technology in cosmetology were presented to the audience.
Application-specific tubes have been developed for use within the framework of Plasmolifting technology. The tubes have been certified and contain substances that guarantee the highest purity of autologous plasma and thus lead to significantly higher efficacy of treatments.
A number of studies have been conducted on the efficacy and safety of Plasmolifting technology in dentistry and cosmetology applications.
The research paper "The use of platelet-rich autoplasma for the treatment of photodermatosis" was published in the journal "Regenerative Surgery". In this publication, Dr. habil. med. Renat Rashitovich Akhmerov describes the first application in international clinical practice of autologous plasma in an injection form.
Clinical trials for testing of Plasmolifting technology have been conducted. Within the trials, volunteer probands with photodermatosis, alopecia and acne were treated by autologous platelet plasma. The results of the trials left no doubt about the efficacy of this type of treatment for the indicated diseases. Additionally, a significant improvement of general condition of skin of the probands was noticeable.
The Russian doctor and researcher R. Akhmerov applied autologous platelet plasma for the treatment of inflammatory diseases and atrophic processes in post-operative period. In this way, prerequisites for the development of an innovative method, which was later called Plasmolifting technology, were created.
A method for the use of autologous platelet gel (APG) derived from autologous platelet-rich plasma (PRP) has been developed. If you add thrombin and calcium to PRP, a sticky clot (gel) quickly forms. This gel has been used both as a hemostatic agent and for covering wound surfaces.
The American maxillofacial surgeon Robert Marks used for the first time in clinical practice blood plasma in the form of a gel. The research results led to a crucial discovery: Platelets contain protein factors that stimulate the processes of cell regeneration.
In the time period, autohemotherapy and autoserotherapy (subcutaneous or intramuscular injection of the patient's own blood serum) becomes the most commonly used auxiliary therapy methods. Before the advent of the antibiotic era, there was no other means of fighting infections.
The Russian surgeon, Professor of Medicine V. F Voyno-Yasenetsky, described the method of autohemotherapy in his book "Outlines of Septic Surgery". During the Russo-Japanese War, he worked as a surgeon in a medical detachment of the Red Cross at a military hospital in Chita, where he used for the first time the autohemotherapy method for the treatment of soldiers of the Imperial Russian Army.
The German doctor and researcher Вodo Spiethoff published his studies in which he described a number of successful cases of treatment of dermatoses, hives, eczema, pemphigus and gangrene ulcers with the autogenous blood serum of patients.
In the same year, the French dermatologist Paul Ravaut described and performed for the first time a method for immediate administration of autologous whole blood, which was called "autohemotherapy”.
This work served as a catalyst for the start of a wider use of autologous blood in clinical practice.
The German surgeon August Bier used autogenous venous blood serum to treat pneumonia. He also found that injection of the patient's own blood accelerates the healing process of bone fractures.
The Austrian doctor Valentin Jez published his data on successful experience in the treatment of erysipelas using a method of subcutaneous administration of autogenous patient blood serum.
The Swedish doctors K. Elfstrøm and A. Grafstrøm described a case of healing of croupous pneumonia in a patient who has received his own blood in the form of subcutaneous injections.