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Diseases of the oral and lip mucosa are quite common pathologies of the tooth and jaw system. The treatment of these pathologies turns out to be difficult due to the peculiarities of the pathological process, its localization and the multifactorial etiological causes.
Taking into account the above-mentioned, the treatment approach does not consist in reducing inflammation, but above all in the targeted and precise stimulation of tissue regeneration processes in a certain area, which in such pathologies is expressed in the prescription of keratoplastic drugs.
An innovative method for the treatment of diseases of the oral and lip mucosa is the Plasmolifting PRP, whose effectiveness has been proven in the treatment of periodontal diseases. Plasmolifting PRP injections suppress inflammation, prevent further tissue loss, restore its color, shape and structure for a longer period of time, also stimulate tissue repair processes, thereby reducing the frequency of exacerbations.
This Plasmolifting PRP procedure is recommended for gingivitis, localized periodontitis, all forms of generalized periodontitis, peri-implantitis, tooth extraction and implantation surgery, as a prophylaxis for periodontal and temporomandibular joint disorders, as well as for cheilitis, including angular cheilitis, and erosive ulcerative lesions of the oral mucosa.
The treatment approach does not consist in the alleviation of inflammation, but primarily in the targeted and precise stimulation of tissue regeneration processes in a specified area. Plasmolifting PRP can be combined with all other procedures for the treatment of diseases of the periodontium, oral and lip mucosa. Its application is completely safe for patients and ensures a maximum physiological response to the procedure. It does not overtax body resources, does not activate the entire immune system, does not cause an allergic reaction and acts on the molecular biological level. Tissues are restored by means of a bio-repair according to the restitution type, i.e., by means of healthy normal tissue in the given area. Addiction risks are excluded in the case of plasma. The stimulation of the regeneration processes is carried out in a targeted manner in the desired areas.
Autologous platelet plasma is currently the richest "treatment cocktail” as a solution of electrolytes, nutrients, metabolites, proteins, vitamins, Signaling substances, biomimetic peptides. But the most important thing is that the alpha granules of platelets contain growth factors.
Growth factors are delivered to tissue in a concentrated form and this leads to accelerated proliferation of epithelial cells, fibroblasts, chondroblasts, osteoblasts, while the activation of osteoclasts is blocked. The cells of the tissue on the other hand produce epithelium, collagen and elastin fibers, hyaluronic acid and intercellular substance.
In lesion foci, young connective tissue is formed, the number of small blood vessels is growing, hemodynamics, oxygenation and regeneration are improving. We observe the restoration of metabolic processes, the improvement of microcirculation and metabolism in tissue cells, normalization of tissue respiration and activation of local immunity.
Plasma is a fluid, so when administered to tissues it spreads quickly into all layers, which is a beneficial factor in the treatment of generalized diseases. For those cases where there is a need to remediate localized diseases, relieve pain, etc., when it is necessary to create a depot of active substances and ensure their maximum long-term presence in a certain area, there is a viscous form of plasma also known as plasmolifting PRP Viscosae.
Fibrin, a protein contained in plasma, has a special feature: When heated to 42° C, it folds in such a way that it takes form of threads or strands. Subsequently, these strands form a fibrin network, which prevents useful plasma components from diffusing beyond the injection site. When plasma is heated to 45 °C in a thermostat and reinjected into the tissue, all proteins, with the exception of fibrin, can renature. And fibrin, which cannot return to its original state and whose strands form a fibrin net, retains all active plasma components in the desired injection area.
Therefore, all useful substances remain in the injection site of the viscous plasma form for a maximum of a long time. With the help of Plasmolifting PRP Viscosae we can strengthen the desired areas, work in a certain area, in which the concentration of the substance is maintained as long as possible, and thus stimulate all regeneration processes precisely in the desired area.
The efficacy of Plasmolifting PRP Viscosae in the treatment of localized processes is 1.5 times higher than that of native plasma. For example, to cure chronic cracks on lips, 2-3 Plasmolifting PRP injections are necessary, while 1-2 prescriptions of Plasmolifting PRP Viscosae are sufficient.
This method is available to dentists of all disciplines. Its implementation does not require any surgical intervention, which makes its application possible by general practitioners, orthopedists, including surgeons, in various clinical situations.
Clinical Case
A patient, V., 25 years old, sought medical attention with symptoms of chronic cracks on the lower lip that did not heal for 5 months. In her medical history, dryness and flaking of the lips were found, caused by severe meteorological and solar radiation factors due to the patient's residence on a seashore. She stressed a bad habit - frequent licking of her lips. During the external examination, about 3 cracks of different lengths and depths were visible in the middle part of the lower lip. The patient repeatedly consulted a dentist, a dermatocometologist, applied various keratoplastic agents, but the measures taken did not lead to the restoration of healthy lip condition.
To cure chronic cracks on the lips, 2-3 injections of Plasmolifting PRP are required, while Plasmolifting PRP Viscosae would only need to be prescribed 1-2 times. The patient was advised to take into account injections according to the Plasmolifting PRP Viscosae method. In the course of the first treatment, injections were administered evenly in both lips, while a plasma depot was placed in the lower lip in the area of the cracks. Already one week after the first injection of the viscous plasma form into the tissue, a significant improvement of the clinical picture is observed, a nearly complete healing of the cracks on the lower lip, the restoration of moisture and pink color of the mucous membrane of the lips occurred. The patient was pleased that she has gotten rid of her symptoms and that her quality of life has improved. In order to strengthen the effect, the Plasmolifting PRP Viscosae procedure was repeated.
One year later, patient V. presented to the clinic again. During the examination, dryness and slight flaking of the lip mucosa were observed, while no cracks on the lips were found over the entire period. At her own request, the patient reapplied the Plasmolifting PRP Viscosae procedure as a preventive measure, as she did not want any further cracks and discomfort.